Retatrutide – For Research Use Only

Available Sizes

• 10mg — $128
• 20mg — $191
• 30mg — $255
• 50mg — $383

About Retatrutide

Retatrutide (LY3437943) is a synthetic tri-agonist peptide simultaneously targeting three G protein-coupled receptors: GLP-1R, GIPR, and GCGR. This unique tri-receptor profile makes it a highly compelling molecule for metabolic research. Studies have examined its effects on energy homeostasis, adipose tissue regulation, insulin secretion dynamics, and hepatic glucose output. The compound activates GLP-1R pathways involved in incretin signaling, GIPR pathways associated with postprandial insulin response, and GCGR pathways linked to hepatic glycogenolysis — providing researchers with a powerful tool to investigate the intersection of these three receptor systems simultaneously.

Research Context

• Tri-agonist GLP-1R/GIPR/GCGR receptor pharmacology
• Comparative studies vs. semaglutide (mono) and tirzepatide (dual)
• Energy homeostasis and adipose tissue metabolism research
• Hepatic glucose output and glycogenolysis pathway studies

Specs

• Purity: 99%+
• CAS: 2381612-46-8
• Form: Lyophilized powder
• Storage: −20°C
• COA: Available every batch

For research use only. Not for human or animal use.